 In 1502, Vasily Kholmsky and Dmitry Ivanovich (son of Ivan III) successfully fought side by side against the Lithuanians in the Smolensk region.In 1505-1506, Kholmsky was in charge of the Big Regiment and was ordered to protect Murom and then Nizhny Novgorod.In 1507, he suffered a bitter defeat from the Tatars near Kazan, only to be sent there once again with a large army to suppress the citizens of that city.