 The route runs east-southeast through more rural land and passes under CSX's Lurgan Subdivision before it heads to the south of the community of Waynecastle, at which point it enters Washington Township.PA 16 runs east past more farms and woods and passes through Zullinger, where it bends east-southeast and heads past residences and a few businesses.The road passes near farm fields before it enters the borough of Waynesboro and becomes West Main Street, where it is lined with homes.