 The CDAI correlated well with protein loss in the bowel in patients with protein losing enteropathy.As most symptoms of Crohn's disease broadly affect quality of life, attempts have been made to incorporate physical, social, and emotional performance characteristics into tests for severity of Crohn's disease.The Inflammatory Bowel Disease Questionnaire (IBDQ) was developed to incorporate elements of social, systemic and emotional symptoms, as well as bowel related symptoms into an activity index.