 PA 10 leaves Parkesburg for Sadsbury Township and becomes Octorara Trail, running northwest through farmland with some homes.The route turns north along the border between West Sadsbury Township to the west and Sadsbury Township to the east as it intersects US 30 (Lincoln Highway) in a commercial area.The road continues north along the township line through farmland with some residences, crossing Buck Run, before heading into forested areas and entering West Caln Township.