 In April 1935, US 122 replaced the PA 42 designation between Oxford and Reading.US 122 began at US 1/PA 472 in the center of Oxford and continued north to Reading, where it ran along the present-day PA 61 alignment to Sunbury and present-day PA 147 to US 11/US 111 in Northumberland.In the 1950s, the southern terminus of US 122 was cut back to Morgantown, and PA 10 was designated along the former alignment of US 122 between US 1/PA 472 in Oxford and PA 23 in Morgantown.