 Marleen van Iersel participated in the 2016 Summer Olympics in Rio together with her teammate Madelein Meppelink, with whom she had teamed since 2014.They made it to the round of 16, and lost to the Swiss team of Heidrich and Zumkehr in 3 sets (21–19, 13–21, 10–15)

Iersel and her wife Myrthe Ramond got married in 2016.The couple have a son.