 MECA-79 mAb inhibits lymphocyte emigration
through HEVs into lymph nodes "in vivo" and lymphocyte adhesion to lymph node and tonsil HEVs "in vitro".Although initially produced against mouse HEVs, the mAb shows a wide crossreactivity among species.The MECA-79 carbohydrate epitope decorates a family of HEV counter-receptors for L-selectin, both in mouse and human16.