 In 2018, DeWitt starred opposite Danny McBride in "Arizona" as well as the second episode in the fourth season of the acclaimed British series, “Black Mirror” for director Jodie Foster.On the small screen, DeWitt was seen in three seasons of the Showtime comedy series, "United States of Tara" alongside Toni Collette.In addition to her role on "United States of Tara", DeWitt also recurred on the critically acclaimed AMC series, "Mad Men", playing Midge Daniels, Don Draper's (Jon Hamm) bohemian mistress in the show's first season.