 Route 112 begins in Huntington at U.S. Route 20, near the junction of the branches of the Westfield River.It heads north from the downtown area, immediately crossing the West Branch and closely following the Middle Branch until it and the North Branch split, at which point it continues to follow the North Branch.In the village of Knightville, Route 112 meets the western end of Route 66, which leads to Northampton.