 After colleague and friend Eric Delko is critically wounded in the line of duty, Calleigh and fellow CSI Ryan Wolfe go to the hospital to give him blood, but they learn that they are too late and that he is on plasma due to catastrophic blood loss.Calleigh and the others take turns at his bedside; she places her cross necklace in his hand to show how much she cares, and is scared for him while he is unconscious (Eric is Roman Catholic).She is the first to talk to Eric after he wakes up, and the first to learn of his impaired memory when he asks for his months-dead sister Marisol.