 In 1999, the Institute received a three-year $1.5 million () challenge grant from the John R. Oishei Foundation along with a $750,000 () award from the Margaret L. Wendt Foundation that established a Structural Biology Center at HWI.All aspects of structural research from isolating the gene that codes for a protein of interest to applying the latest crystallographic methods are now possible here.Through this Center, HWI scientists were able to create new and improved crystal growth methods including the development of a novel and patented high-throughput robotic crystallization technique for expediting and optimizing the crystallization process.