 As an active member and later president of the ADIR (Association of Deportées and Internées of the Résistance),
she filed lawsuits against Nazi war criminals, then took part in the rise of the political movement launched by her uncle, Rassemblement du peuple français (Rally of the French People).In 1958, de Gaulle-Anthonioz worked with the cabinet of André Malraux of which her husband was a member.She met Father Joseph Wresinski, then chaplain of the town of Noisy-le-Grand.