 Beforehand, Sales was the network's Washington correspondent from 2001 to 2005.The stories which she covered included the Iraq War, the 2004 presidential election, Guantanamo Bay and Hurricane Katrina

In 2011, Sales was appointed anchor of the ABC's flagship prime time current affairs program, "7.30".She has interviewed every living Australian prime minister and many world leaders and celebrities, including Hillary Clinton, the Dalai Lama, Aung San Suu Kyi, Sir Paul McCartney, Patti Smith, and Salman Rushdie.