).The freeway has a cloverleaf interchange with I-80, crosses over the Union Pacific's Laramie Subdivision and US 30 (Lincolnway), and has a four-ramp partial cloverleaf interchange with US 30, which here is also part of I-80 Bus..

I-25 continues north along the western edge of the city of Cheyenne and along the eastern edge of Francis E. Warren Air Force Base, which is served by the next three interchanges.