 On 3 August 1985, route 45 was converted to one man operation with the AEC Routemasters replaced by Leyland Titans.Having been operated by London Central out of Camberwell garage since first tendered in 1987, on 11 November 2017 it was taken over by Abellio London's Walworth garage with Alexander Dennis Enviro400 MMCs introduced.On 15 June 2019, the route was withdrawn between King's Cross and Elephant & Castle.