 A descendant of the Euro-African Ga people, he attended the all-boys' Anglican boarding school, the Adisadel College, then joined John Holt trading company, rising to the position of Regional Manager and representing the company in Kumasi.Later, Griffiths-Randolph resigned and travelled to London in order to further his education.He successfully completed his legal education at Inner Temple In 1952, after which he returned to Ghana.