 Jefferies appeared on comedy panel shows such as "Never Mind the Buzzcocks", "Have I Got News for You", "The Heaven and Earth Show" and "8 Out of 10 Cats", the US comedy panel show "The Green Room with Paul Provenza" and Comedy Central's "@midnight".He has also been featured on various radio programmes, including BBC Radio 5 Live's Saturday morning sports show, "Opie and Anthony", and "Fighting Talk".In 2015, he starred in Australian film "Me and My Mates vs the Zombie Apocalypse" with comedians Greg Fleet and Alex Williamson.