 Spinosad has recently been used in oral preparations (as Comfortis) to treat "C. felis", the cat flea, in canines and felines; the optimal dose set for canines is reported to be 30 mg/kg.Spinosad is sold under the trade names, Comfortis, Trifexis, and Natroba.Trifexis also includes milbemycin oxime.