 From 1921 until 1925, Murphy played for the Columbus Senators of the International league.Through his stint with Columbus, Murphy continued to be an excellent hitter, hitting .397 in 1925 at the age of 33, which won him the league's batting title.In 1927, he played for the Rochester Tribe (who would later go on to be called the Rochester Red Wings ), playing for manager George Stallings and alongside former MLB star Rabbit Maranville.