 In addition to the test's high specificity, the use of two samples ensures that the diagnostic procedure has a high (>99%) test sensitivity as well.Cartridge Based Nucleic Acid Amplification Test (CBNAAT) using the GeneXpert Platform, and TrueNat are rapid molecular tests for TB diagnosis and Rifampicin resistance detection .This test is the first choice of diagnostic test for high risk population, children, contacts of drug resistant cases and PLHA(Patient Living With HIV AIDS) .