 Shortly after the outbreak of the Second World War, the Laté 521 were taken over by the French Navy, who typically operated the type as a long distance maritime patrol aircraft.None survived the conflict due to intentional sabotage by the retreating German forces.The Laté 521 was the basis of the single Laté 522 "Ville de Saint Pierre" civil airliner, and the three Laté 523 navalized variants.