 Treatments geared to the activation of the ventromedial prefrontal cortex were therefore suggested for individuals and parent-child relationships affected by PTSD.The right half of the ventrolateral prefrontal cortex, being active during emotion regulation, was activated when participants were offered an unfair offer in a scenario.Specific deficits in reversal learning and decision-making have led to the hypothesis that the ventromedial prefrontal cortex is a major locus of dysfunction in the mild stages of the behavioral variant of frontotemporal dementia.