 He married Julia A. Lockwood (1837–1900) of Connecticut.She also worked as a physician and was known as "Madame Grindle" and they had a child, Minnie Grindle (1862–1938) who would later marry Alonzo Grey, a physician; and John Wesley Grindle.On August 27, 1868, Susannah Lattin died post-partum at his illegal abortion and adoption clinic at 6 Amity Place (now West Third Street) in New York City.