 PNT) domain which forms oligomer partners with itself as well as other transcription factors (e.g.FLI1) and is required for ETV6's transcriptional repressing activity; b) the central regulatory domain; and c) the C-terminal DNA-binding domain, ETS, which binds to the consensus DNA sequence, 5-GGAA/T-3 within a 9-to-10 bp sequence, in the target genes it regulates.ETV6 interacts with other proteins that regulate the differentiation and growth of cells.