 In the case of head wounds, surgical intervention was implemented for investigating and diagnosing the nature of the wound and the extent of the impact while bone splinters were removed preferably by scraping followed by post operation procedures and treatments for avoiding infection and aiding in the healing process.Evidence has been found in prehistoric human remains from Proto-Neolithic and Neolithic times, in cave paintings, and the procedure continued in use well into recorded history (being described by ancient Greek writers such as Hippocrates).Out of 120 prehistoric skulls found at one burial site in France dated to 6500 BCE, 40 had trepanation holes.