 With his associate Johann Veit (1852–1917), he is credited with establishing the groundwork for contemporary gynecological pathology and histology.In the 1870s the two men introduced the surgical biopsy as a necessary diagnostics tool.From their biopsies, they demonstrated that there were too many cases of unnecessary surgeries for cervical cancer, proving that physicians were often incapable of detecting cancer without the aid of a biopsy.