 Led by Ralph Bock from the Max Planck Institute of Molecular Plant Physiology in Germany, researchers studied genetically modified tobacco in which the transgene was integrated in chloroplasts.A transplastomic tabacco plant generated through chloroplast mediated transformation was bred with plants that were male sterile with an untouched chloroplast.The transplastomic plants were engineered to have resistance to the antibiotic spectinomycin and engineered to produce a green fluorescent protein molecule (GFP).