 Active in the second half of the 17th century, Santa Cruz leaves the best of his work in the Cathedral of Cusco, as he is commissioned to decorate the walls on the side of the choir and the arms of the transept.In the picture of the "Virgin of Bethelem", located in the choir, there is a portrait of the bishop and patron Manuel de Mollinedo y Angulo that help quite to the developing of the Cusco Painting School and the city.Such is the fame reached by the Cusqueña painting of the 17th century, which during the following century produces a singular phenomenon that, curiously, left its mark not only in art but in the local economy.