 The double stranded RNA confers protection to the transgenic potato plant via a RNA interference methodology, where consumption of the plant tissue by the potato beetle would result in silencing of key genes required by the beetle for survival.There was a high level of protection conferred, the leaves of the transplastomic potato plant were mostly unconsumed when exposed to the adult beetles and larvae.The investigation also revealed an 83% killing efficacy for larvae that consumed the leaves of the transplastomic plant.