 This suggests albendazole is most effective for treating both "T. trichiura" and "N. americanus".Cryotherapy by application of liquid nitrogen to the skin has been used to kill cutaneous larvae migrans, but the procedure has a low cure rate and a high incidence of pain and severe skin damage, so it now is passed over in favor of suitable pharmaceuticals.Topical application of some pharmaceuticals has merit, but requires repeated, persistent applications and is less effective than some systemic treatments.