 He was later appointed regent of the Apostolic Penitentiary (7 December 1911), canon of the Liberian Basilica (1915), assessor of the Holy Office (8 December 1916), and canon of St. Peter's Basilica (6 March 1917).Elevated to the College of Cardinals before receiving his episcopal consecration, Perosi was created Cardinal-Deacon of "S. Eustachio" by Pope Pius XI in the consistory of 21 June 1926.He was named Pro-Secretary of the Sacred Consistorial Congregation on 10 February 1928, rising to become full Secretary on the following 1 November.