 He acceded to the title in 1780 after the death of his father George Venables-Vernon, first Baron Vernon of Kinderton.Vernon was educated at Westminster School and at Trinity Hall, Cambridge, proceeding MA in 1755.He served as a Whig Member of Parliament for Weobley from 1757 to 1761, Bramber from 1762 to 1768 and Glamorganshire from 1768 to 1780.