 On January 22, 2010, Arredondo signed a minor league contract with the Cincinnati Reds.He underwent Tommy John surgery (UCL reconstruction) in February and spent the summer of 2010 training at the Reds' facility in Goodyear, Arizona.On July 23, 2010, the Reds purchased the contract of Arredondo and placed him on the 60-day DL after designating Corky Miller for assignment.