 The genome of "Natronomonas pharaonis" consists of three circular replicons, the chromosome which is 2,595,221 bp in length, a typical haloarchaeal 131-kb plasmid, and a unique multicopy 23-kb plasmid.Its chromosome has a high G + C content (63.4%).Also, a high proportion of acidic amino acids (average 19.3%) is found in the proteins of "N. pharaonis" which results in low isoelectric points (average pI 4.6).