 Hillesheim’s neighbours are Dittelsheim-Heßloch, Dolgesheim, Dorn-Dürkheim, Frettenheim, Gau-Odernheim and Eimsheim.Hillesheim has two centres, "Ortskern", or municipal core, and "Bahnhof", or railway station.In the outlying centre of Bahnhof stands the former railway station once served by the Osthofen–Gau Odernheim line and used together with the neighbouring municipality of Dorn-Dürkheim.