 Berankis started the 2010 season by competing at the 2010 SAP Open, where he defeated Robby Ginepri in the first round, 6–7, 6–2, 6–3 and Björn Phau in the second round 7–6, 6–3.In the quarterfinals, he lost to then-world number 11 Fernando Verdasco 6–3, 7–6.Berankis then failed to qualify to the 2010 Delray Beach main draw, losing in the first round in the qualifying draw.