 The highway was designated MD 2 in the late 1920s and extensively improved in the late 1930s and 1940s.The first portion of MD 765 was designated in the early 1950s when MD 2's bypass of Prince Frederick opened.Further sections of MD 765 were assigned between Sunderland and Owings when MD 2 was reconstructed north of MD 4 in the mid-1960s.