 In 1846, during the Mexican–American War, Osio fled to Honolulu, where he lived until 1849.After returning to Monterey in 1850, Osio sold his Rancho Punta de los Reyes Sobrante to Andrew Randall, who also bought Rancho Punta de los Reyes, and Rancho Aguas Frias.Osio returned to Mexico in 1852.