 The general regulatory requirements for all U.S Food and Drug Administration (FDA) regulated foods are found in section 21 of the U.S. Code of Federal Regulations (CFR) Part 117.Section 113.40 lists specific requirements for aseptic processing and packaging systems, including specifications for equipment and instrumentation.One requirement of the FDA regulations is that all thermal processing operations must be conducted under the operating supervision of an individual who has completed an FDA-approved course of instruction on control of thermal processing systems, container closures, and acidification procedures.