 In rare cases, tenoxicam and other NSAIDs can contribute to thrombotic events, Stevens-Johnson Syndrome, and toxic epidermal necrolysis.It is not recommended that women who are trying to conceive, who are pregnant, or who are breastfeeding take tenoxicam.Tenoxicam can be taken in the first and second trimester when necessary, but it is a contraindication in the third trimester.