 It was known that chemical communication between embryo and mother was essential for a successful pregnancy in mammals.However, little was known about the details of the process, before R. Michael Roberts and Fuller W. Bazer began a collaboration to elucidate on these relationships.After a period of intensive joint efforts, lasting 16 years, each has continued over the past several years, to make important independent contributions, at Texas A&M University and at the University of Missouri.