 Among his key discoveries, Fuller isolated the uterine protein uteroferrin, a hematopoietic growth factor that influences the survival of the neonate and may be useful in treating diseases, such as leukemia and osteoporosis.He determined that estrogen in pigs and interferon-t in ruminant species, are the signals for pregnancy maintenance.The ability of interferon-t to suppress transcription of the estrogen receptor gene, provides a model for potential treatment of estrogen-dependent tumors.