 Irene Gattilusio

Irene Gattilusio, born Eugenia Gattilusio (died 1 June 1440) was a Byzantine Empress consort by marriage to John VII Palaiologos, a Byzantine Emperor in 1390.She was a daughter of Francesco II of Lesbos (a maternal grandson of Andronikos III Palaiologos) and Valentina Doria.