 The protein encoded by ACAD8 is a mitochondrial protein belongs to the acyl-CoA dehydrogenase family of enzymes, which function to catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branched-chain amino acids.ACAD8 functions in catabolism of the branched-chain amino acid valine.ACAD8 functions as a homotetramer and has an overall structure is similar to other acyl-CoA dehydrogenases.