 Here, the route crosses the Bullpasture River and winds its way towards the Cowpasture River, after which it enters the village of Head Waters.From Head Waters, U.S. 250 ascends in elevation on a winding and mountainous path to enter Augusta County, Virginia over Shenandoah Mountain.Continuing on U.S. 250 east provides access to Interstate 64 and Interstate 81 near Staunton.