 He opened a cut near Forbes' eye in the sixth round, going on to win by unanimous decision in 12.`

On June 6, 2008, Floyd Mayweather, Jr. announced his first of many subsequent retirements from boxing, effectively ending talk of a rematch.De La Hoya faced Manny Pacquiao (47–3–2) on December 6, 2008 at the MGM Grand in Las Vegas.Presented by Golden Boy Promotions and Top Rank, Inc., the bout was a twelve-round, non-title fight at the welterweight limit.