 After leaving Hightown, U.S. 250 ascends Monterey Mountain before descending to the county's seat of Monterey.In Monterey, U.S. 250, the county's major east-west route, intersects the county's major north-south route, U.S. 220.Continuing eastward, U.S. 250 follows the flow of Crab Run through mountainous terrain towards McDowell.