 He relinquished the IBF title and defended the WBO title against undefeated Genaro Hernández (32–0–1), who relinquished the WBA super-featherweight title to fight De La Hoya.Hernandez quit after six rounds because of a broken nose.In his sixth and final defense of the WBO lightweight title, he knocked out Jesse James Leija (30–1–2) in two rounds at New York's Madison Square Garden.