 At the 2010 US Open, after knocking out Australian Peter Luczak in the first round, Stakhovsky battled into the third round with a five-set win over American qualifier Ryan Harrison, coming back from triple match point down in a fifth-set tiebreaker to win a match marked by dramatic serve-and-volleying, rallies at net, and leaping overheads from both players.In the 3rd Round, Sergiy retired in the second set trailing Feliciano López with an infected toe.Sergiy reached a career high ranking of 31 on 27 September 2010.