 Bursicon is a 30 kDa neurohormone heterodimeric protein which is encoded by CG13419 gene and made of two cysteine knot subunits, Burs-α and Burs-β.It is nondialyzable and loses its activity in alcohol, acetone, some proteases and trichloroacetate, renaturates after adding ammonium sulfate.Bursicon plays a very important role in insect wing expansion during the last step of metamorphosis