 Castiel knocks Gadreel out and comforts Dean when the torture they have Crowley perform to bring forth Sam's mind proves too much for Dean.Castiel is furious to learn that the angel possessing Sam is actually Gadreel, blaming him for all the evil in the universe, but Dean calms him down.When Gadreel proves resistant to their efforts to expel him, Dean tries to have Castiel possess Sam to let him know of the situation but he can't without Sam's permission, and furthermore has no way to gain it due to Sam’s mind being kept under by Gadreel.