 This marked their first Super Bowl appearance in 50 years, since Super Bowl IV.On February 2, 2020, in Hard Rock Stadium in Miami Gardens, Florida, the Chiefs played against the NFC's top seed, the San Francisco 49ers.Following halftime when both teams were tied at 10 points, Mahomes threw 2 interceptions in back to back drives in the 3rd and 4th quarters, resulting in the 49ers having a 20-10 lead with under 12 minutes remaining in the game.