 Clements-Mann graduated from Texas Tech University in 1968 and received her medical degree from the University of Texas in 1972.She also received a doctorate in tropical medicine from the University of London in 1975 and a master's degree in public health, specifically epidemiology, from Johns Hopkins University in 1979.Clements-Mann was an assistant professor at the University of Maryland School of Medicine from 1979 to 1985.