 The squadron was the first of the 90th Wing's four Minuteman squadrons to activate, as construction on launch facilities continued until the middle of 1964.Beginning in June 1973, its Minuteman I missiles began to be replaced by LGM-30G Minuteman IIIs, which could carry up to three reentry vehicles.In 2001 in compliance with the Strategic Arms Reduction Treaty, these missiles were limited to a single reentry vehicle

In 1996 the squadron won the Blanchard Trophy as the best missile operations squadron at the Guardian Challenge missile competition and the Samuel C. Phillips Award as the best missile squadron in the command.