 Hampl worked as an editor of "Minnesota Monthly" from 1973 to 1975 and as a freelance writer and editor from 1975 to 1979.Between 1979 and 1996, she was a visiting assistant professor, associate professor, and professor of English at the University of Minnesota, Minneapolis, where she is now the Regents Professor and McKnight Distinguished Professor and teaches fall semesters in the English department's MFA program.Hampl has taught courses such as Heroic Poetics, History in a Personal Voice, Reading Across Genres, Contemporary American Poets, Introduction to Creative Writing and Introduction to Fiction Writing.