 Since 2005, she has been closely involved with the establishment of the Southern African Legal Information Institute, a web-based law reporting system that is part of the Free Access to Law Movement.In 2013, O'Regan was appointed by Premier Helen Zille as a commissioner, with Vusi Pikoli, of the Khayelitsha Commission, tasked with investigating the alleged breakdown of policing in Khayelitsha township.The Commission released its report in August 2014.