 Bartholomew is known for his bas reliefs, marble busts and statues, and medallions in the neo-classical style.His earliest recorded work is a medallion of poet Lydia Sigourney (1847).Among his best-known works are "Blind Homer Led by the Genius of Poetry" (1851, now in the Metropolitan Museum), "Eve", "Campagna Shepherd Boy" (Peabody Institute), "Genius of Painting", "Youth and Old Age", "Evening Star", "Eve Repentant" (Wadsworth Atheneum), "Washington and Flora", "A Monument to Charles Carroll" (near Baltimore), "Bellsarius at the Porta Pincinia", and "Ganymede".