 Hanson finished the 2010 campaign with a 10–11 record, 3.33 ERA, and 1.17 WHIP.He set a career-high in innings-pitched with 202.2, surrendering 182 hits while striking out 173 batters and walking 56.On June 12, Hanson set a new career high of 14 strikeouts in a game against the Houston Astros, which matched the most strikeouts recorded by a pitcher at Minute Maid Park.