 The DePaul Spartans competes in the Big North Conference, following a reorganization of sports leagues in Northern New Jersey by the New Jersey State Interscholastic Athletic Association.Before the NJSIAA's 2010 realignment, the school had competed in the Northern Hills Conference an athletic conference made up of private and public high schools located in Essex, Morris and Passaic counties.There are over 20 varsity sports for boys and girls in the school.