 Guillermo del Toro, Don Murphy, and Joel Silver are the executive producers of this film.Theatrically released on June 4, 2010, the film received generally positive reviews from critics but grossed just $27 million against a $30 million production budget.Genetic engineers Clive Nicoli and Elsa Kast hope to achieve fame by splicing animal DNA to create hybrids for medical use at the company N.E.R.D.