 He was named papal Governor of Bologna after the sack of Rome, and continued to serve in that office after being appointed Bishop of Tortona by Pope Clement VII.During his years as Bishop of Tortona, he participated in the Coronation of Charles V as Emperor in Bologna in 1532, and was absent as papal legate or nuncio in Germany (1532).He was named a cardinal on 10 December 1539 by Pope Paul III, who then named him Legate in Parma and Piacenza.