 Thynne was again a member of parliament, for Wiltshire in 1559, for Great Bedwyn in 1563, for Wiltshire again in 1571, and for Heytesbury in 1572.He was High Sheriff of Wiltshire for 1568–1569, and Custos rotulorum and a Justice of Peace for Wiltshire from 1558–1559 until his death.When he died in 1580, Thynne left manors in Wiltshire, Gloucestershire, Somerset and Oxfordshire, and property in the cities of London, Westminster, and Bristol.