 Peyton Manning's fourth career NFL win came via two touchdown throws to Marvin Harrison, an Edgerrin James rushing score, a 74-yard interception return touchdown by Tony Blevins, and a Mike Vanderjagt field goal.Doug Flutie of the Bills had one touchdown throw and two picks.Manning erupted in the first half, completing 14 of 17 throws with three touchdown throws to Marvin Harrison along with an Edgerrin James rushing score while the Patriots shot themselves in the foot with penalties, ultimately committing fifteen fouls eating up 135 yards and trailing the Colts 28–7.