 Empiric treatment should be started within 60 minutes of being admitted.Periodic monitoring should be done to see if the empiric treatment is working, or if a more target therapy should be initiated.In people with cancer who have febrile neutropoenia (excluding patients with acute leukaemia), oral treatment is an acceptable alternative to intravenous antibiotic treatment if they are haemodynamically stable, without organ failure, without pneumonia and with no infection of a central line or severe soft-tissue infection.