 In 1625 Lane was elected Member of Parliament for Wycombe and was re-elected in 1628.After an eleven-year period during which King Charles I ruled without parliaments, Lane was re-elected for Wycombe in April 1640 for the Short Parliament.He was re-elected in November 1640 to the Long Parliament and remained supporting the parliamentarian cause until ejected under Pride's Purge in 1648.