 People receiving large quantities of oxidative drugs such as dapsone or sulfasalazine are more prone to have degmacytes.The underlying cause of degmacytes is a result of the splenic macrophages removing Heinz bodies from the membrane of red blood cells, which results in a "bitten" appearance of the cell.The diagnosis of degmacytes is performed by using a peripheral blood smear to analyze the red blood cells in the blood.