 Bacterial permeability family member A1 (BPIFA1/SPLUNC1) is an innate protein that is secreted basolaterally from healthy, but not asthmatic, human bronchial epithelial cultures (HBECs).It suppresses airway smooth muscle contractility by binding to and inhibiting the Ca2+ influx channel Orai1.BPI; BPIL1; BPIL2; BPIL3; CETP; LBP; LPLUNC1; LPLUNC3; LPLUNC4; PLTP; PLUNC; SPLUNC2;