 Lupo developed artistically under the guidance of Vittorio Cavalleri, and also attended night courses at the Accademia Albertina.He worked within the tradition of late 19th-century Piedmontese Naturalism, influenced in his landscapes by the works of Delleani.His debut at the Turin Società Promotrice di Belle Arti in 1901 with three studies from life was followed by regular participation in the major national events.