 On 22 September 2015, Dybala was called for the first time for the Argentina senior team by manager Gerardo Martino, but his first appearance was on 13 October 2015, coming off the bench to replace Carlos Tevez in the 75th minute during a 2018 FIFA World Cup qualifying match against Paraguay.In May 2016, he was omitted from Argentina's 23-man squad for the Copa América Centenario.Although Juventus insisted that they would not release Dybala for the 2016 Summer Olympics in Rio de Janeiro, he was included in Martino's 35-man preliminary under-23 squad for the tournament on 24 May; he was not included in the final squad for the tournament, however.