 At San Remo two days later, on 5 November, Frederick entirely lost his voice and experienced severe pain throughout his throat.Upon examination, Dr. Hovell discovered a new growth under the left vocal cord; when the news reached William and the German government, it caused great consternation.The following day, Mackenzie issued a bulletin stating that while there was no immediate danger to the Crown Prince, his illness had "unfortunately taken an unfavourable turn," and that he had requested advice from other specialists, including the Austrian professor of laryngology Leopold Schrötter and Dr. Hermann Krause of Berlin.