 Ardmore is located at (35.004746, -86.851402).The city is concentrated along Tennessee State Route 7 (Main Street), which runs congruent with Alabama State Route 53 along the state line before veering northwestward to its intersection with Interstate 65 and U.S. Route 31 in the western part of the city.US 31 connects Ardmore with Elkton, Tennessee, which lies to the northwest, and Tennessee State Route 110 connects Ardmore with Fayetteville to the northeast.