 Together, they discovered and identified the hormone aldosterone, the last of a series of naturally occurring biologically potent steroid hormones to be isolated and identified between the 1920s to the 1950s, after the androgens, oestrogens, and glucocorticoid hormones.Aldosterone is part of the mechanism that regulates blood pressure, and causes conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure.It is thought to be responsible for 15 per cent of cases of high blood pressure.