 "Hitchcock" centers on the relationship between film director Alfred Hitchcock (Anthony Hopkins) and his wife Alma Reville (Helen Mirren) during the making of "Psycho", a controversial horror film that became one of the most acclaimed and influential works in the filmmaker's career.In 1959, Alfred Hitchcock opens his latest film, "North by Northwest", to both critical and commercial success, but is troubled by a reporter's insinuation that he should retire.Seeking to reclaim the artistic daring of his youth, Hitchcock turns down film proposals, including "Casino Royale" and "The Diary of Anne Frank", in favor of a horror novel called "Psycho" by Robert Bloch, based on the real-life crimes of murderer Ed Gein.