 Various lymphomas can exhibit the microscopic appearance, including plasmablastic cells, and presentation of PBL.These lymphomas can usually be differentiated from PBL by further examinations of the plasmablasts for various marker proteins and determining other factors that favor the diagnosis of these lymphomas rather than PBL, as indicated in the following descriptions.Unlike PBL, the plasmablastic cells in anaplastic lymphoma kinase-positive large B-cell lymphoma strongly express the product of the "ACVRL1" gene, i.e.