 On 26 November 2015, Chalobah was given his first Napoli start in a 1–0 victory over Club Brugge in the UEFA Europa League group stage tie.On 10 December 2015, Chalobah scored his first Napoli goal in a 5–2 win over Legia Warsaw, scoring Napoli's first.On 6 January 2016, Chalobah finally made his Serie A debut in a 2–1 victory against Torino, replacing Marek Hamšík in the 89th minute.