 Both receptors couple the same cellular signal transduction pathways, PLC and PLA2, that lead to an accumulation of inositol phosphate and Ca2+ within the postsynaptic cell.The 5-HT2C receptors are the only G-protein coupled receptors known to undergo a post-transcriptional process of RNA editing.The 5-HT2C receptor gene is found on the X-chromosome, Xq24.