 Most of its major events are temporary exhibits related to some aspect of Mexico's cultures.In 1997 it had an exhibition called La Ruta de la Esclavo tracing the history of African slavery in Mexico during the colonial period.For Day of the Dead 2011, the museum held an event called Tzompantli Gráfico where twenty artists including Fupete from Italy and Lucas Varela from Argentina, created modern skull images to arrange similar to that of a Mesoamerican tzompantli or skull-rack.