 The serotonin receptor agonist mCPP has a significant affinity for 5-HT2C receptors.mCPP patients experience multiple side effects due to non-selectivity over 5-HT2A and 5-HT2B receptors.The absence of the hypophagic (reduced food consumption) effect of mCPP in 5-HT2C receptor knockout mice suggests that this effect is mediated through 5-HT2C receptor activation.