 Between 1996 and 1997, McPhedran held the position of Strategic Counsel with the Friends of Women's College Hospital.McPhedran was the Chief Commissioner of the Saskatchewan Human Rights Commission and was the Ariel Sallows Chair in International Human Rights, University of Saskatchewan College of Law in 2007.From 1994 to 1996, McPhedran was Corporate Director of Health Partnerships and International Liaison at the Women's College Hospital in Toronto, where she negotiated the College's designation as a World Heath Organization Collaborating Centre in Women's Health in the Pan American region.