 During the rule of the Damascus-based Caliph Mu'awiya I (), founder of the Umayyad Caliphate, Amr married his daughter Ramla and they lived in Medina, the former capital of Amr's father.Amr and Mu'awiya likely maintained friendly ties for much of the caliph's reign, but latent tension may have developed between them due to Mu'awiya's suspicions of Amr's ambitions for the caliphate and the influence of their Umayyad kinsman Marwan ibn al-Hakam over Amr to pursue the caliphate.The modern historian Asad Q. Ahmed views these claims as difficult to "verify or refute".