 He served as cardinal protector of The Holy House of Loreto from December 11, 1580 until his death.On December 19, 1583, he opted for the deaconry of Sant'Angelo in Pescheria.He participated in the papal conclave of 1585 that elected Pope Sixtus V. The new pope named him Governor of "Montis Castelli Tudertini" in 1585.