 This often compromises experiments in basic life science, leads to misleading drug-screening results on efficacy and toxicity, and produces cells that may lack the characteristics needed for developing tissue regeneration therapies.The future of cell culturing for fundamental studies and biomedical applications lies in the creation of multicellular structure and organization in three-dimensions.Many schemes for 3D culturing are being developed or marketed, such as bio-reactors or protein-based gel environments.