 Giessibl spent most of his professional career improving atomic force microscopy, and published papers on ground breaking experiments, instrumentation
and theoretical foundations
of atomic force microscopy.Giessibl is the inventor of the qPlus sensor, a sensor for Non-contact atomic force microscopy that relies on a quartz cantilever.His invention has enabled atomic force microscopy to obtain subatomic spatial resolution on individual atoms and submolecular resolution on organic molecules.