 Esoro studied Political Science at University of Abuja.Esoro's acting career started in 2005, when she was cast by her friend Bovi to feature in the soap opera "Extended Family", however she became more notable when she featured in another television series titled "Clinic Matters" playing a character named "Nurse Abigail".In a 2013 list compiled by "Vanguard", Esoro was listed as one of top ten best new actresses in the film industry.