 Perillo was signed from the practice squad to the active roster on October 14, 2015.He recorded his first NFL reception, a 21-yard sideline catch from Aaron Rodgers in a Week 6 game against the San Diego Chargers.Perillo had a breakout game against the Detroit Lions in Week 10, where he hauled in five receptions for 58 yards and scored his first NFL touchdown late in the fourth quarter.