 She uses genomic methods, natural history collections and computational modeling to understand the phylogeny, phylogeography, and polyploidy of angiosperms.She has published over 400 scientific papers, and among her most cited contributions are papers on the role of genetic and genomic attributes in the success of polyploids.In 2016, Soltis was elected as a member of the National Academy of Sciences and the American Academy of Arts and Sciences in 2017.