 This point is still contested and represents another major dispute in the field.To further refute the Cieplak effect, Houk puts forth a system in which Cieplak's model predicts the wrong product distribution trend.In the case of substituted trans-decalones, electron-withdrawing substituents equatorial at C4 should discourage equatorial attack and yield more axial product, since the ring C–C bonds are deactivated for donation into the forming C-Nuc bond.