 Nurbanu accused Safiyye and her retainers of causing Murad's impotence with witchcraft.Several of Safiye's servants were tortured by eunuchs in order to discover a culprit.Court physicians, working under Nurbanu's orders, eventually prepared a successful cure, but a side effect was a drastic increase in sexual appetite—by the time Murad died, he was said to have fathered over a hundred children.