 While the Marvel Universe is presumably as large as the non-fictional universe comic book readers inhabit, for all intents and purposes the Local Group is the universe; practically all action takes place in it.The Skrull Empire is located in the Andromeda Galaxy, the Kree Empire in the Greater Magellanic Cloud, which is a satellite of the Milky Way galaxy in which Earth, of course, is found, and the Shi´ar Empire is located somewhere between them in one of the smaller galaxies (perhaps the Triangulum Galaxy); frequently, these three empires are quoted as the main political powers "in the universe".Similarly, the Local Group seems to be the only affected area when the Annihilation Wave cut its bloody swath "across the universe".