 Limbs have been lost or reduced independently over two dozen times across lizard evolution, including in the Anniellidae, Anguidae, Cordylidae, Dibamidae, Gymnophthalmidae, Pygopodidae, and Scincidae; snakes are just the most famous and species-rich group of Squamata to have followed this path.Most lizard species are harmless to humans.Only the largest lizard species, the Komodo dragon, which reaches in length and weighs up to , has been known to stalk, attack, and, on occasion, kill humans.