 Slough resigned in April 1862 and was replaced by Major John M. Chivington.A second regiment, the 2nd Colorado Infantry, was organized in February 1862, with four existing companies of independent militia joining the volunteer service and forming the nucleus of the new regiment, which primarily fought Indians during its existence, although battalions from the regiment fought at the Battle of Honey Springs in present-day Oklahoma.Much of the regiment was later consolidated with the 3rd Colorado Infantry Regiment and reformed into the 2nd Colorado Cavalry.