 His descendants played important roles in the politics of the Duchy of Milan and as cardinals in the Catholic Reformation.In 1916 the head of the family was granted the title Prince of Angera.The best-known members of the family were the cardinals and Archbishops of Milan; Carlo (1538–1584), who was canonized by Pope Paul V in 1610, and Federico (1564–1631), who founded the Ambrosian Library.