 After crossing the whole city, it turns into the Rosario–Córdoba Highway.The avenue was inaugurated in 1868 as "Bulevar Argentino", as part of a program of the municipality (created 6 years before) to beautify the city, then home to 23,000 residents, and which also included the opening of Oroño Boulevard (then "Bulevar Santafesino").Its current name is an homage to Carlos Pellegrini (president of Argentina from to 1890 to 1892).