 At the end of 2006, when De Nederlandse Opera staged the three Mozart-Da Ponte operas conducted by Ingo Metzmacher, de Niese sang Susanna in "The Marriage of Figaro" and Despina in "Così fan tutte".In 2009, de Niese made her Covent Garden debut in The Royal Opera's production of Handel's "Acis and Galatea", directed by choreographer Wayne McGregor and recorded on DVD.Beginning on 31 December 2011 and continuing through January 2012, de Niese appeared as Ariel in "The Enchanted Island", a pastiche opera created by Jeremy Sams for the Metropolitan Opera.