 In 2015, Ameen was one of the eight central characters in the initial run of the Netflix series Sense8, produced by the Wachowskis and J. Michael Straczynski.However, conflicts with the Wachowskis resulted in his replacement with Toby Onwumere after filming two episodes of the second season in 2016.In 2018, Ameen starred as a young Jamaican named "D" in the film "Yardie".