 During the Dominican Republic Crisis of April/May 1965, the 354th deployed the 353rd TFS and more than 400 people and 18 F-100s to Ramey AFB, Puerto Rico, and San Isidro AB, Dominican Republic on 2 May.The squadron returned on 28 May.The Vietnam War drained the 354 TFW at Myrtle Beach, starting in 1965 with its flying squadrons and support personnel being deployed for several years to Spain, Japan, South Korea and South Vietnam.