 Before the 12th century, a parish church dedicated to Saint Lawrence had occupied the site of the cathedral.Even as this church was constructed, the town was already spreading northwards down the hill, leaving the plaza somewhat isolated on the highest edges of town, thus restricting its attraction to the townsfolk, a disadvantage which the local bishops for years attempted to reverse by granting the cathedral special religious privileges.The cathedral was at the height of its significance during the middle and end of the thirteenth century, when it and the attached Palazzo dei Papi di Viterbo was the home of the papal throne following its flight from Rome and prior to its resettlement in Avignon.