 At the end of the 13th century there were three altars in honor of Saints Bartholomew, Innocent and Margaret, in the ancient church of San Salvatore, which had been built by the aristocratic della Croce family which had owned land in the area since 1317.In 1464, Stefano Della Croce in his will ordered his heirs to build a chapel in honor of the Virgin in the main church of San Salvatore.During the Late Middle Ages, Busto Garolfo became a feud first of the Maggi family, then of the Arconati family and later, of the Losetti family.