 NC 22 splits from NC 24 and NC 27 in Carthage after looping around the Moore County courthouse.Exiting Carthage as McNeill Street, NC 22 joins US 15/501 for a one-mile (1.6 km) stretch before running independently to its southern terminus at NC 2 in Southern Pines.The route ends just shy of NC 2's interchange with U.S. 1.