 She was the daughter of Francisco Diego Pascual de Borja y Aragón y Centelles, 8th duque de Gandía, and of Artemisa María Ana Teresa Gertrudis, princesa de Doria de Melfi.Her elder sister Magdalena was the wife of Philippe François, 1st Duke of Arenberg.Her second marriage, on July 20, 1664, was to her cousin, Pedro Antonio Fernández de Castro Andrade y Portugal, 8th conde de Villalba, 10th conde de Lemos, 7th marqués de Sarria.