 It was destroyed by Lautaro in 1554, and rebuilt and destroyed again by Lautaro in 1555.According to the 2002 census of the National Statistics Institute, Penco spans an area of and has 46,016 inhabitants (22,366 men and 23,650 women).Of these, 45,361 (98.6%) lived in urban areas and 655 (1.4%) in rural areas.