 Most of his enemies are criminally insane, and locked in the Miskatonic Mental Institution (a play on Arkham Asylum, and H. P. Lovecraft's Miskatonic University in the city of Arkham).While Professor Night has been active as a hero since the 1930s, he and Twilight spent almost thirty years in suspended animation when their souls were stolen by one of their supernatural foes, explaining why they appear younger than their history with Supreme would suggest.Professor Night and Supreme have long enjoyed a professional partnership and are also close friends, fully aware of each other's secret identity.