 Research activities cover a wide spectrum of topics, ranging from basic molecular analyses of neuronal processes to clinical studies on novel therapies of neurological and psychiatric disorders in patients.The central aim of all these studies is to understand basic molecular and cellular processes in brain function, to analyze their pathological dysfunction in psychiatric and neurological diseases, and ultimately to develop novel therapies for these disorders.The Department of Neurogenetics, led by Klaus-Armin Nave, uses transgenic techniques, natural and engineered mouse mutants and the tools of molecular and cellular biology to study neural development and the pathomechanisms of neurodegenerative diseases.