 Then in 1981, Harrison conducted the first open fetal surgery on a fetus to correct a dangerously advanced urinary tract obstruction.Throughout the 1980s and 90s, Harrison and his associates continued to develop and further refine fetal intervention techniques to treat a range of birth defects and to do so with less invasive means such as fetendo and fetal image-guided surgery.During the 1980s, Harrison worked closely with obstetricians, anesthesiologists, geneticists, sonographers, surgical sub-specialists, neonatologists, nurses, and ethicists to lay the foundation for what would be the multidisciplinary UCSF Fetal Treatment Center.