 It is in the eastern section of Vilnius, along the left bank of the Neris River, with the river running along the whole western side of the district.The Antakalnis eldership is the second-largest in Vilnius, with an area of .One of the greatest Lithuanian Baroque masterpieces, the Roman Catholic Church of St. Peter and St. Paul, is in Antakalnis, as is Sapieha Palace ("Sapiegų rūmai").