 The transfer of ownership and publication responsibilities required the physical transfer of manuscripts from Welch's office, which fell to the director of the Rockefeller Institute, Simon Flexner, who carried the abandoned manuscripts from Baltimore to New York City in a suitcase.The first issue published by the Rockefeller Institute appeared in February 1905, with Flexner serving as editor, and the journal has been published regularly since then.Although the journal was adopted by the Rockefeller Institute as a venue for publication of the Institute's own research, it also accepted submissions from outside.