 An ally of Frederick Barbarossa in his war against the Lombardy communes, it took part in the destruction of Tortona in 1115, obtaining certain privileges in exchange.Around 1300 Castelnuovo became part of the Duchy of Milan.In 1570 it changed name from Castelnuovo di Tortona to Castelnuovo Scrivia, and become a fief of the Marini family and, after their extinction in 1778, of the Centurione family.