 He transferred to A.C. Milan in 1992 winning the "scudetto" in both of his seasons at the Milanese club (1992–93 and 1993–94), as well as another Supercoppa Italiana winners medal in 1993; in addition to these domestic titles, he won an UEFA Champions League and an UEFA Super Cup in 1994 during his time with the club.However he was not a first team regular making only 9 league appearances in 2 seasons.In July 1994, De Napoli moved to his final football club; Reggiana.