 It has also been found, using comparative proteomic analysis with "B. pseudomallei", that rpoS regulates eight oxidative responsive proteins including ScoA (a SCOT subunit) not previously known for oxidative stress response involvement.The regulatory effect in this case is RpoS down regulation of SCOT expression in response to oxidative stress in "B. pseudomallei".RpoS-dependent genes involved in changes in cell membrane permeability and general cell morphology mostly belong to the "osm" family of genes.