 A complete understanding of the mechanisms for neural differentiation and proliferation could prove to be crucial to the treatment of neurodegenerative diseases.Towards this end, many researchers are attempting to control the differentiation and proliferation of neural stem cells "in vivo" by altering the expression of key genes such as presenilins and the sonic hedgehog pathway.Colin Kolles

Colin Kolles (born Călin Colesnic 13 December 1967 in Timișoara) is a Romanian-German former team principal and managing director of the Hispania Racing F1 Team, previously holding a similar position at the team known under the names Jordan, Midland, Spyker and Force India from 2005 to 2008.