 The Nemadji River empties into Lake Superior in an industrial neighborhood at Allouez Bay in the city of Superior's east-side neighborhood of Allouez and Wisconsin Point.Most of the rivers' length flows in Douglas County, WI, entering near Foxboro and exiting in East End, Superior, near Loons Foot Boat Landing, USH 2/53, and the BNSF Taconite Plant

Nemadji comes from the Ojibwe language, "ne-madji-tic-guay-och" ("Nemanjitigweyaag" in the current spelling), meaning "left-hand river," opposed to the Saint Louis River, which when viewed from Allouez Bay is the "right-hand river.