 Her maternal grandparents were Heinrich XXIV, Count Reuß-Ebersdorf and Karoline Ernestine von Erbach-Schönberg, and her paternal grandparents were Ernst Friedrich and Antoinette of Braunschweig-Wolfenbüttel.In Coburg on 17 November 1798, she married Alexander of Württemberg.The couple settled in Russia, where Alexander, as a maternal uncle of both Emperors Alexander I and Nicholas I made a military and diplomatic career.