 A primary purpose of IUPHAR is providing global free access to a major, on-line repository of characterization data for receptors, ion channels, enzyme target classes and drugs through the Committee on Receptor Nomenclature and Drug Classification (NC-IUPHAR), established in 1987.The Guide to Pharmacology established in 2012 superseded the earlier IUPHAR-DB.This is a joint endeavor with the British Pharmacological Society, and has been supported by the Wellcome Trust.