 Elisabetta de Gambarini was born 7 September 1730 in Holles Street, St Marylebone, Middlesex, England.She was born to Charles Gambarini (died 1754), Counsellor to the Landgrave of Hessen-Kassel and Joanna (Giovanna Paula) Stradiotti (died 1774).Her father was a nobleman from Lucca, Italy.