 US 30 then splits from Interstate 376 and US 22 in Wilkinsburg, and the I-376/US 22 concurrency continues to the Pennsylvania Turnpike in Monroeville, where I-376 ends.East of Interstate 376, US 22 continues east as a primary arterial highway between Pittsburgh and major population centers in central Pennsylvania, such as Johnstown, Altoona, State College, Huntingdon, Fredricksburg, and Lewistown.The entire length between Pittsburgh and US 220 and Interstate 99 just west of Altoona was widened to at least four lanes by summer 2011.