 If the catheter is removed without giving antibiotics, 38% of people may still develop endocarditis.A systematic review has found evidence that in cancer patients, there may be no benefit to giving antibiotics before inserting a long-term central venous catheter to prevent Gram positive catheter-related infections.However, flushing the catheter with a solution containing an antibiotic and heparin may reduce catheter-related infections in this population, most likely when the risk of infection is high.