 The Santa Ana Freeway (Interstate 5) heads north to Los Angeles, and south towards Southern Orange County and San Diego.The Garden Grove Freeway (State Route 22) runs along near Santa Ana's northern border, connecting Long Beach to the west and the City of Orange to the east.The Costa Mesa Freeway (State Route 55) travels south to Costa Mesa; and then north to the Riverside Freeway (State Route 91), providing a connection to Riverside.