 In the beginning Assisi fell under the rule of Perugia and later under several despots, such as the soldier of fortune Biordo Michelotti, Gian Galeazzo Visconti and his successor Francesco I Sforza, dukes of Milan, Jacopo Piccinino and Federico II da Montefeltro, lord of Urbino.The city went into a deep decline through the plague of the Black Death in 1348.The city came again under papal jurisdiction under the rule of Pope Pius II (1458–1464).