 To truly be called mezcal, the liquor must come from certain areas.States that have certified mezcal agave growing areas with production facilities are Durango, Guanajuato, Guerrero, Oaxaca, San Luis Potosí, Puebla, Michoacan, Tamaulipas, and Zacatecas.About 30 species of agave are certified for use in the production of mezcal.