 US 23, which is known as Orby Cantrell Highway for most of its course, is a four-lane divided highway that follows Corridor B of the Appalachian Development Highway System through Southwest Virginia.The U.S. Highway serves as the main east–west highway of Scott County and the primary north–south highway of Wise County.US 23 runs concurrently with US 58 from Weber City to Duffield and with US 58 Alternate between Big Stone Gap and the independent city of Norton.