 During the administration of President George W. Bush, Czarencki held a number of appointed leadership positions at the U.S. Department of Labor.Beginning in June 2001, she served as Deputy Assistant Secretary for Intergovernmental Affairs, responsible for outreach to state and local officials.In June 2003 she was appointed Director of the Office of the 21st Century Workforce, which hosted conferences and workshops and published various materials to highlight the strategic workforce initiatives of Secretary of Labor Elaine Chao.