 The university was closed in 1636 soon after opening the Jesuit College in Ostroh.In the 16th century, all higher schools of the Polish-Lithuanian Commonwealth were under influence of the Catholic or Protestant nobles.To counter this influence, Count Konstanty Ostrogski, one of the most influential people in the Crown of Poland (and later a major partisan of the Orthodox faith against the Union of Brest), founded a large school in his estate in Ostroh in what is now Ukraine.