 By the beginning of the 18th century, Sisakan was associated with the Armenian military leader David Bek, who led the liberation campaign of the Armenians of Syunik against Safavid Persia and the invading Ottoman Turks.David Bek started his battles in 1722 with the help of thousands of local Armenian patriots who liberated Syunik.In 1750, Sisakan/Gharakilisa became part of the newly formed Karabakh Khanate.