 SR 49 and US 15 continue east concurrent into downtown Clarksville, where the highway passes through the Clarksville Historic District.After passing through the downtown area, SR 49 and US 15 leave the town of Clarksville by crossing the John H. Kerr Reservoir, an impoundment of the Roanoke River that is also known as Buggs Island Lake, on the Phillip Saint Julian Wilson Bridge and a causeway.The bridge, which contains lights underneath used for nighttime fishing, includes a brief passage through Halifax County due to the thalwegs of the Roanoke and Dan Rivers, which were used to set the county boundaries, converging just south of Clarksville.