 "Otome wa Boku ni Koishiteru" revolves around the main protagonist Mizuho Miyanokouji, a male high school student.After Mizuho's grandfather dies, his will is reviewed, which explains his desire to have his grandson transfer to Seio Girls' Academy, the same one his own mother attended and his ancestors founded.Abiding by the will, Mizuho cross-dresses to attend the school.