 On 27 August 2012 Hoshide robotically captured and berthed JAXA's HTV-3 uncrewed cargo spacecraft, on 30 August he ventured outside the ISS alongside Williams for his first spacewalk, over the eight hour, 17-minute spacewalk, the two astronauts prepared a Main Bus Switching Unit (MBSU) for replacement on a later spacewalk and switched some cables on the Russian Orbital Segment ahead of the launch and docking of the future Nauka laboratory module.On 5 September he and Williams went outside the station again, for a 6-hour, 28-minute spacewalk to replace the MBSU the two had prepared for replacement on the last spacewalk, they also replaced a camera on Canadarm-2

On 16 September 2012, Paldalka, Revin and Acaba departed the station onboard Soyuz TMA-04M, following which Hoshide, Williams and Malenchenko became part of the Expedition 33 crew, with Williams taking command of the station for the increment.They were later joined by Soyuz TMA-06M crewmembers Oleg Novitsky and Evgeny Tarelkin, both of Roscosmos, and NASA astronaut Kevin Ford.