 On 24 May 2016, Ayestarán was appointed Valencia manager until 30 June 2018.However, he was sacked on 20 September with the team in last place in the league table, having lost all four games of the season and 8 of his overall 12 fixtures.On 27 September 2017, Ayestarán replaced Manolo Márquez as the new UD Las Palmas manager.