 Natoire's father Florent Natoire, a sculptor, gave him his fundamental training in drawing, then sent him to Paris in 1717 to complete his training, first in the atelier of Louis Galloche (1670–1761), "peintre du Roi" and professor at the Académie royale de peinture et de sculpture, and then in the atelier of François Lemoyne, whose training shaped Natoire's style.In 1721 he obtained the Prix de Rome with a "Sacrifice of Manoah to obtain a son".On 30 June 1723 he was appointed a "pensionnaire" at the French Academy in Rome, at the time lodged in the Palazzo Mancini, where he arrived in October.