 The most effective anti-epileptic medication for JME is valproic acid (Depakote).Due to valproic acid's 
high incidence of fetal malformations, women of child-bearing age are started on alternative medications such as Lamotrigine, levetiracetam.Carbamazepine may aggravate genetic generalized epilepsies and as such its use should be avoided in JME.