 Anne married Sir Henry Portman (1596-1621) of Orchard Portman, Somerset, Member of Parliament and Keeper of Roche Forest, on 20 July 1615.Anne's second husband was Sir Robert Kerr of Ancram who became Earl of Ancram in 1633.In November 1621 Prince Charles had written to Anne's mother, Elizabeth Countess of Derby, in favour of Sir Robert Kerr, who had leave from his court duties to visit her.