 Born in New York City, Lawrence moved to Philadelphia in 1720, where, for the rest of his life, he was engaged in the mercantile business.In 1730, after being associated with James Logan, Lawrence formed a partnership with Edward Shippen; Shippen & Lawrence became one of Philadelphia's leading firms.Apart from his life in private business, Lawrence held several positions of trust in the city, including serving as mayor for six one-year terms, as city councilman and alderman, and as judge of the county court.