 In 1873 Guinness founded the "East London Institute for Home and Foreign Missions", the root of the "Regions Beyond Missionary Union".In 1877 he founded the Livingstone Inland Mission, which worked in Congo, Argentina and Peru.His son Dr. Henry Grattan Guinness (1861–1915) founded the Congo-Balolo Mission in 1888 and co-founded the Congo Reform Association in 1904.