 However within a few decades, an acute hypercalcemia syndrome with a relative good outcome was identified by Cuthbert Cope in 1936 (now called Cope syndrome), and in 1949 Charles H. Burnett identified a similar but more severe syndrome, with chronically high blood calcium levels and poor outcomes.When the true cause of most gastric ulcers was identified and drugs other than antacids were developed to treat heartburn – namely acid-reducing drugs like H2-receptor antagonists or proton pump inhibitors – the incidence of milk-alkali syndrome greatly diminished.However, as a result of increased osteoporosis awareness and the routine use of calcium supplements to prevent it, the incidence has again increased.