 The easiest and most effective way to remove botfly larvae is to apply petroleum jelly over the location, which prevents air from reaching the larva, suffocating it.It can then be removed with tweezers safely after a day.White glue mixed with pyrethrin or other safe insecticides and applied to the spot of swelling on the scalp will kill the larvae within hours, as they must keep an air hole open, so will chew through the dried glue to do this, consuming the insecticide in the process.