 It has similar vasoactive properties in other areas of the body, particularly the lungs.Unlike many other ergolines, such as ergotamine, nicergoline is not associated with fibrosis 

It is used for vascular disorders such as cerebral thrombosis and atherosclerosis, arterial blockages in the limbs, Raynaud's disease, vascular migraines, and retinopathy.Nicergoline has been registered in over fifty countries and has been used for more than three decades for the treatment of cognitive, affective, and behavioral disorders of older people.