 The study did not find a link between late-life onset scintillating scotoma and stroke.Symptoms typically appear gradually over 5 to 20 minutes and generally last less than 60 minutes, leading to the headache in classic migraine with aura, or resolving without consequence in acephalgic migraine.Many migraine sufferers change from scintillating scotoma as a prodrome to migraine to scintillating scotoma without migraine.