 Keeslar is known for his roles in "Waiting for Guffman", "The Last Days of Disco"  and "Scream 3", and the miniseries "Frank Herbert's Dune" and "Stephen King's Rose Red".Keeslar starred in the 2008 ABC Family series "The Middleman".He established a strong working relationship with South Coast Repertory in Costa Mesa, California, where he performed plays and staged readings.