 hypersensitivity to ovalabumin), a TP receptor antagonist decreased the number of eosinophils infiltrating lung as judged by their content in Bronchoalveolar lavage fluid and in a mouse model of dust mite-induced astha, deletion of "TBXA2R" prevented the development of airways contraction and pulmonary eosinophilia responses to allergen.Another TP receptor agonists likewise reduced airway bronchial reactivity to allergen as well as symptoms in volunteers with asthma.The TP receptor appears to play and essential role in the pro-asthmatic actions of leukotriene C4 (LTC4)