 Richards is named as a depositor on 27 crystal structure entries in the Protein Data Bank, including the now-obsoleted ribonuclease S (), hen egg lysozyme (), SH3 domains (), the ion-channel-forming alamethicin () (), and mutants of ribonuclease S (e.g., ;), of Staphylococcal nuclease (e.g., ;), and of lambda repressor in complex with DNA ().The Department of Molecular Biophysics and Biochemistry ("MB&B") that Richards founded and chaired at Yale, which amalgamated the medical school Biochemistry and the university Molecular Biophysics departments, was considered to have "quickly gained pre-eminent stature.